Enhesa GHS+ Chemical Hazard Assessment framework overview
Learn how we generate and maintain Chemical Hazard Assessments (CHAs)—including the process steps, data requirements, evaluation criteria, and assessor qualifications.
📚 Table of Contents
- Step 1 – Confirm Chemical Identity
- Step 2 – Screen Against Chemical Lists
- Step 3 – Endpoint-Level Hazard Assessment
- Step 4 – Overall Chemical Hazard Categorization
- Step 5 – Quality Assurance & Verification
- Step 6 – Ongoing Maintenance
- References
- Appendix A: SciveraLENS GHS+ Chemical Hazard Assessment Framework – Criteria by Endpoint
- Appendix B: Chemical Lists Monitored by Enhesa Sustainable Chemistry and Available for Screening in SciveraLENS
Introduction
Since SciveraLENS’s founding in 2008, our toxicologists have performed comprehensive chemical hazard assessments using procedures and criteria established by government authorities, accreditation bodies, and widely accepted toxicology practices.
This page outlines the steps, data requirements, evaluation criteria, and assessor qualifications used by the Enhesa Sustainable Chemistry team to generate and maintain a Chemical Hazard Assessment (CHA). These assessments evaluate the human and environmental health characteristics of industrial chemicals.
🧪 Hazard Assessment Overview
Our toxicologists follow a structured process that:
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✅ Confirms the identity of the chemical under assessment
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✅ Screens the chemical against authoritative and regulatory lists to identify early indicators of potential concern
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✅ Assesses hazard characteristics across 24 human and environmental health endpoints, plus relevant physical hazard endpoints
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✅ Determines an overall hazard category for the chemical, integrating list reviews and endpoint assessment results
Figure 1-1: SciveraLENS GHS+ Chemical Hazard Assessment Process Flow Diagram
We’ve built and updated the GHS+ Chemical Hazard Assessment Process (“GHS+”) on a foundation of the broadly-accepted approach, endpoints, and criteria from the following leading documented references for best practices in this discipline:
💡 Reference Foundations for GHS+
Enhesa GHS+ Chemical Hazard Assessment Process
Enhesa Sustainable Chemistry’s GHS+ process ensures a thorough and scientifically grounded Chemical Hazard Assessment (CHA). The steps below outline our standardized approach.
Step 1 – Confirm Chemical Identity
Step 1 – Confirm Chemical Identity
To begin a CHA, our toxicologists first verify the identity of the chemical using a set of accepted methods. This step ensures a reliable connection between the substance and its relevant data across physical-chemical, human health, and environmental endpoints.
Primary Identifier:
- CAS RN (Chemical Abstract Service Registry Number): The most widely used unique identifier, linking chemicals to data. While there are over 279 million CAS RNs, we focus on the ~400,000 relevant to consumer products and industrial applications in our SciveraLENS Chemical Data Repository.
Other Identifiers (if CAS RN is missing or conflicting):
- EC Number (ECHA)
- US EPA PMN (Pre-Manufacture Notification Number)
- SMILES notation (molecular structure)
- Other authoritative references
Why This Matters:
- Accurate chemical identification ensures compatibility with regulatory lists, minimizes ambiguity from naming conventions, and supports the use of modeling tools and analog analysis.
Step 2 – Screen Against Chemical Lists
Step 2 – Screen Against Chemical Lists
Next, we screen the chemical against a curated collection of 600+ lists within SciveraLENS, organized into:
- Regulatory Lists
- Authoritative Lists
- Restricted Substance Lists (RSLs)
- Screening & Watch Lists
- Preferred & Organizational Lists
- Chemical Groups
- Informational/Inventory Lists
These lists help identify initial indications of concern for human or environmental health endpoints.
Important Note: List screening is not equivalent to a full hazard assessment. While helpful for early prioritization, only a full assessment can determine the true hazard profile.
Chemical Groups: Many lists flag groups of chemicals (e.g., “mercury and its compounds”) rather than individual substances. Our team maps group listings to specific chemicals—a complex but essential task to provide clarity for users.
Step 3 – Endpoint-Level Hazard Assessment
Step 3 – Endpoint-Level Hazard Assessment
Toxicologists assess each endpoint using multiple data types:
- Authoritative Lists
- Regulatory Lists
- Experimental Data
- Modeled Data
- Analogous Data
- Expert Judgment
Data Sources Include:
- NIH/NLM (e.g., PubChem)
- ECHA REACH dossiers
- US EPA databases
- NTP reports
- IARC monographs
- ToxPlanet
- Peer-reviewed literature
Modeling Tools:
- OECD QSAR Toolbox
- US EPA EpiSuite
- US EPA T.E.S.T.
- PBT Profiler (referenced but no longer supported)
Best Practices:
- Analog Read-Across: Used when direct data is missing.
- Expert Judgment: Toxicologists assess data quality and consistency.
- Data Reliability: High-quality experimental data is preferred. Klimisch scores and other indicators are used, but expert review is central.
- Weight-of-Evidence: When data conflict, we apply a precautionary principle, classifying at the highest supported hazard level.
🧪 Endpoints Assessed in the GHS+ Chemical Hazard Assessment
We evaluate three endpoint categories: Human Health, Environmental Health, and Physical-Chemical Properties. Each includes Core and Supplemental endpoints.
🧍♀️ Human Health Endpoints
✅ Core Endpoints
Required for an overall hazard category other than “Gray” (i.e., insufficient data):
- Carcinogenicity
- Mutagenicity / Genotoxicity
- Developmental Toxicity
- Reproductive Toxicity
- Endocrine Activity
➕ Supplemental Endpoints
Contribute to the hazard profile; data gaps are permitted:
- Acute Oral Toxicity
- Acute Dermal Toxicity
- Acute Inhalation Toxicity
- Respiratory Sensitization
- Dermal Sensitization
- Dermal Irritation
- Eye Irritation
- Systemic Toxicity (Single and Repeat Dose)
- Neurotoxicity (Single and Repeat Dose)
- Sensory Irritation
- Aspiration Potential
🔎 To avoid a “Gray” score, all Core Human Health Endpoints must be conclusively assessed. Supplemental endpoints support the overall picture but are not mandatory for a conclusive score.
🌿 Environmental Health Endpoints
✅ Core Endpoints
Required for a conclusive overall environmental hazard category:
- Persistence
- Bioaccumulation
- Acute or Chronic Aquatic Toxicity
➕ Supplemental Endpoint
- Mobility (assessed and documented; not factored into scoring)
🔎 To avoid a “Gray” score, data must be conclusive for Persistence, Bioaccumulation, and at least one aquatic toxicity endpoint.
🔥 Supplemental Physical-Chemical Endpoints
Assessed when relevant and data are available:
- Flammability
- Reactivity
- Environmental Transformation Products
⚠️ If a transformation product is persistent, bioaccumulative, or toxic, it may affect the scoring of related endpoints like Persistence or Toxicity.
🚦 Hazard Communication: The GHS+ Traffic Light System
Each endpoint and overall hazard assessment is communicated using a color-coded system. This process ensures our partners and stakeholders receive transparent, science-driven insight into chemical hazards, supporting safer and more sustainable decision-making.
📊 Table 2-1: SciveraLENS GHS+ Endpoint-Level Hazard Assessment Conditions
| Color Code | Hazard Level | Meaning |
|---|---|---|
| 🟢 Green | Low Hazard | Indicates a low hazard for the specific endpoint or overall chemical. |
| 🟡 Yellow | Moderate Hazard | Indicates a moderate hazard. |
| 🔴 Red | High Hazard | Indicates a high hazard. |
| ⚫ Black | Very High Hazard | Indicates a very high hazard. |
| ⚪ Gray | Insufficient Data | Data are insufficient for assessment. |
| 🔵 Blue | Assessment in Progress | No concerns found during list screening; assessment not yet complete. |
| ◑ Half-Gray | Modeled/Analog Data | Indicates use of modeled, analogous, or expert judgment data in the score. |
🔎 This traffic light system provides a clear, intuitive way to interpret chemical hazard assessments at both the endpoint and overall level.
🧮 Step 4 – Overall Chemical Hazard Categorization
While individual endpoint results provide detailed insight into hazard type and severity, an overall hazard category enables efficient comparison, prioritization, and alternatives assessment.
To assign this category, Enhesa Sustainable Chemistry uses a rules-based system implemented in SciveraLENS. The system evaluates all endpoint-level assessments to determine the Overall Hazard Category.
Step 4 – Overall Chemical Hazard Categorization
📊 SciveraLENS Overall Chemical Hazard Categories and Rules
| Category | Criteria |
|---|---|
| 🟢 Green – Highly Preferred | – All endpoints show conclusive or limited-evidence low hazard – No data gaps for Core or Supplemental Endpoints |
| 🟢🟡 Green/Yellow – Preferred | – All Human Health Core Endpoints are low hazard with no data gaps – One or more Supplemental Endpoints are moderate hazard – One Environmental Fate Endpoint may be high if others are low – No endpoints show very high hazard – No more than three Supplemental data gaps |
| 🟡 Yellow – Acceptable | – One or more Supplemental Endpoints are high or very high hazard – No Core Endpoints are high or very high hazard – No Environmental Fate Endpoints are high if paired with moderate Human Health or Ecotoxicity hazards – No more than three Supplemental data gaps – No Core data gaps |
| 🔴 Red – High Concern | – One or more Human Health Core Endpoints are high or very high hazard, or – Two or more Environmental Health Core Endpoints are high or very high hazard (e.g., Persistence + Bioaccumulation), or – Very High Persistence or Bioaccumulation combined with very high acute or high chronic Human Health hazards |
| ⚪ Gray – Unable to Categorize | – One or more Core Endpoint data gaps, or – Four or more Supplemental Endpoint data gaps |
| 🔵 Blue – In Process | – Assessment not yet complete |
Step 5 – Quality Assurance & Verification
🛡️ Step 5 – Enhesa Sustainable Chemistry Quality Assurance & Verification
GHS+ hazard assessments are completed within our Chemical Data Repository (CDR), the engine behind SciveraLENS. Key QA features include:
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✅ Quantitative scoring integration for endpoints like acute and aquatic toxicity
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📚 Source tracking to document all reviewed references
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🔄 Workflow stages based on endpoint types (e.g., CMRD, PBT) and status (Research → Assess → QA → Complete)
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👥 Dual review process: A board-certified toxicologist performs a full second review before finalization
🔎 Once verified, the hazard assessment is marked “Complete” and fully aligned with the GHS+ framework.
Enhesa Sustainable Chemistry continuously improves the GHS+ methodology by engaging external board-certified toxicologists and scientific authorities, ensuring the framework evolves with new science and stakeholder input.
Step 6 – Ongoing Maintenance
🔄 Step 6 – Ongoing Maintenance of GHS+ Hazard Assessments
Hazard assessments are actively maintained through a structured, recurring update process:
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🗂️ List monitoring and updates propagate automatically across affected chemicals
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🔬 New hazard data is evaluated and used to revise endpoint scores
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🔔 User alerts notify SciveraLENS users of changes to chemicals of interest
📅 The GHS+ framework is a living system, designed to stay up-to-date with the latest data and scientific consensus.
References
📚 3. References
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US Environmental Protection Agency Design for Environment Program
Alternatives Assessment Criteria for Hazard Evaluation, Version 2.0 (2011) -
National Academy of Sciences
A Framework to Guide the Selection of Chemical Alternatives (2014) -
United Nations
Globally Harmonized System (GHS) of Classification and Labelling of Chemicals, 10th Revised Edition (2023) -
NSF International / Green Chemistry Institute / American National Standard
NSF/GCI/ANSI 355 – 2011: Greener Chemicals and Processes Information
(May require purchase or institutional access) -
Global Electronics Council & TÜV Rheinland
Criteria for the Sustainability Assessment of Network Equipment for the EPEAT® Ecolabel and TÜV Rheinland Green Product Mark (2021)
(Specific criteria documents are available via GEC’s EPEAT website or through partner certification bodies)
Appendix A: SciveraLENS GHS+ Chemical Hazard Assessment Framework – Criteria by Endpoint
SciveraLENS GHS+ Chemical Hazard Assessment Framework – Criteria by Endpoint
Human Health Endpoints – Chronic
| Hazard | GHS+ Criteria | Very High | High | Moderate | Low |
| Carcinogenicity | GHS | GHS Category 1A – Known human carcinogen (largely based on human evidence) | GHS Category 1B – Presumed human carcinogen (largely based on animal evidence) | GHS Category 2 – Suspected human carcinogen | |
| GHS+ Qualitative Assessment of Available Data | Experimental and modeling data may be used. | Experimental and modeling data may be used. | Experimental and modeling data may be used. Modeling data may not be used alone. Negative modeling with negative Mutagenicity/Genotoxicity and repeated dose Systemic Toxicity. | ||
| Mutagenicity/Genotoxicity | GHS | GHS Category 1A | GHS Category 1B | GHS Category 2 | |
| Known to induce heritable mutations in germ cells of humans | Presumed to induce heritable mutations in germ cells of humans. Experimental and modeling data may be used. | Suspected of inducing heritable mutations in the germ cells of humans. Experimental and modeling data may be used. | Experimental and modeling data may be used. Modeling data may not be used alone. | ||
| Authoritative Lists | EU Category 1 | EU Category 2 | EU Category 3 | ||
| Developmental and Reproductive Toxicity (scored as separate endpoints) | GHS | GHS Category 1A | GHS Category 1B | GHS Category 2 | |
| Known human reproductive toxicant | Presumed human reproductive toxicant | Suspected human reproductive toxicant | |||
| Assessment of Available Quantitative Data (quantitative values are used for guidance only, considered in the context of maternal toxicity in relation with reproductive / developmental effects) | NOAEL/LOAEL oral (mg/kg/day): <50 | NOAEL/LOAEL oral (mg/kg/day): 50-250 | NOAEL/LOAEL oral (mg/kg/day): >250 | ||
| NOAEL/LOAEL dermal (mg/kg/day): <100 | NOAEL/LOAEL dermal (mg/kg/day): 100-500 | NOAEL/LOAEL dermal (mg/kg/day): >500 | |||
| NOAEL/LOAEL inhalation (vapor/gas) (mg/L/day): <1 | NOAEL/LOAEL inhalation (vapor/gas) (mg/L/day): 1-2.5 | NOAEL/LOAEL inhalation (vapor/gas) (mg/L/day): >2.5 | |||
| NOAEL/LOAEL inhalation (dust/mist/fume) (mg/L/day): <0.1 | NOAEL/LOAEL inhalation (dust/mist/fume) (mg/L/day): 0.1-0.5 | NOAEL/LOAEL inhalation (dust/mist/fume) (mg/L/day): >0.5 | |||
| Qualitative Assessment of Available Data | Experimental and modeling data may be used. | Experimental and modeling data may be used. | Experimental and modeling data may be used. Modeling data may not be used alone | ||
| Authoritative Lists | EU Category 1 | EU Category 2 | EU Category 3 | ||
| California Proposition 65 – listed | |||||
| Endocrine Activity | GHS+ Qualitative Assessment of Available Data | Evidence of endocrine disrupting activity in appropriate assays. Evidence or endocrine activity and related human health effect. SVHC endocrine chemicals. When C, D, R and TOST are H and in vivo effect is endocrine-related. | Evidence of endocrine activity. When D, R and/or TOST are M with in vivo endocrine-related effects (e.g., thymus, thyroid). Listed on relevant lists; indication of endocrine activity in studies (modeling and in vitro). Modeling indicates “active”. | No evidence of activity (no binding, perturbation, or evidence of endocrine-related adverse effects) in appropriate assays and no structural alerts. Need negative data (modeled, in vitro, and in vivo) for key EATS (estrogenic, androgenic, thyroid, steroidogenic) endocrine pathways. | |
| Authoritative Lists | EU Category 1 | EU Category 2 | |||
| Hazard Lists | ChemSec SIN Listed | TEDX Listed |
Human Health Endpoints – Acute
| Hazard | GHS+ Criteria | Very High | High | Moderate | Low |
| Acute Oral Toxicity (LD50, rat) | GHS | GHS Category 1 or 2 | GHS Category 3 | GHS Category 4 | GHS Category 5 or “not classified” |
| Qualitative Assessment of Available Data (Experimental or modeled) | LD50 ≤ 50 mg/kg | 50 mg/kg< LD50 ≤ 300 mg/kg | 300 mg/kg < LD50 ≤ 2000 mg/kg | LD50 > 2000 mg/kg | |
| Acute Dermal Toxicity (LD50, rabbit) | GHS | GHS Category 1 and 2 | GHS Category 3 | GHS Category 4 | GHS Category 5 or “not classified” |
| Qualitative Assessment of Available Data. | LD50 ≤ 200 mg/kg | 200 mg/kg < LD50 ≤ 1000 mg/kg | 1000 mg/kg < LD50 ≤ 2000 mg/kg | LD50 > 2000 mg/kg | |
| Acute Inhalation Toxicity (LC50, rat) | GHS | GHS Category 1 and 2 | GHS Category 3 | GHS Category 4 | GHS Category 5 or “not classified” |
| Qualitative Assessment of Available Data. | Vapor – < 2 mg/L; Dust/mist - LC50 ≤ 0.5 mg/L | Vapor- 2 mg/L < LC50 ≤ 10mg/L; Dust/mist - 0.5 mg/L < LC50 ≤ 1.0 mg/L | Vapor -10 mg/L < LC50 ≤ 20mg/L; Dust/mist - 1 mg/L < LC50 ≤ 5mg/L | Vapor – LC50 > 20 mg/L; Dust/mist LC50 > 5mg/L | |
| Dermal Irritation | GHS | GHS Category 1, 1A, B and C | 2-Irritant | 3-Mild irritant | “Not Classified” |
| Qualitative Assessment of Available Data including Modeling Results (e.g., Toxtree “me” data cards) | 1A – Evidence of irreversible damage to skin in human following exp of up to 3 min and up to 1 hr observation; or in animal experience or test data; pH extremes of ≤ 2 and ≥ 11.5. 1B,C-Evidence of irreversible damage to skin in human following exp of > 3 min and up to 4 hrs and observations of up to 14 days, or in animal experience or test data; pH extremes of ≤ 2 and ≥ 11.5 — NOTE: If only GHS Category 1 is specified (but not 1A or 1B or 1C) then descriptive data of the hazard will be used to determine score. | Evidence of reversible damage to skin following exp of up to 4 hrs (human experience or data or animal experience or data). Modeling data may be used. | Evidence of reversible damage to skin following exp of up to 4 hrs in animal experience or test data. Modeling data may be used. | Adequate data available, and negative studies, no structural alerts, GHS not classified. Modeling data may not be used alone. | |
| Acute Eye Irritation | GHS | GHS Category 1 | GHS Category 2A | GHS Category 2B | |
| Qualitative Assessment of Available Data | Damage to the eye which is not fully reversible within 21 days (human data/experience) or positive animal experience or test data in at least 1 animal | Changes in the eye which are fully reversible within 21 days (human data/experience) or positive animal experience or test data in at least 2 animals — NOTE: If only GHS Category 2 is specified (but not 2A or 2B) then descriptive data of the hazard will be used to determine score. Modeling data may be used. | Evidence of mild eye irritation in human experience or data or animal experience or test data indicating complete reversibility of lesions within 7 d — NOTE: If only GHS Category 2 is specified (but not 2A or 2B) then descriptive data of the hazard will be | Adequate data available, and negative studies, no structural alerts, GHS not classified. Modeling data may not be used alone. | |
| Sensory Irritation | GHS+ Qualitative Assessment of Available Data | RD50 ≤ 5 ppm | 5 ppm < RD50 ≤ 1500 ppm | RD50 > 1500 ppm | |
| GHS STOT H335 |
Human Health Endpoints – Other
| Hazard | GHS+ Criteria | Very High | High | Moderate | Low |
| TOST – Single Exposure (Specific target organ systemic toxicity following single exposure) | GHS | GHS Category 1 | GHS Category 2 | GHS Category 3 | GHS Category “Not Classified” |
| Qualitative Assessment of Available Data | Reliable evidence of a significant adverse effect on specific organ/systems or systemic toxicity in humans or animals. Oral ≤ 300mg/kg; Dermal ≤ 1000 mg/kg; Inhalation -vapor/gas – ≤ 10 mg/L/4hr; dust/mist/fumes – ≤ 1.0mg/L/4hr | Evidence of a harmful adverse effect on specific organ/systems or systemic toxicity from animal studies or humans. Oral – > 300 to ≤ 2000mg/kg; Dermal – > 1000 to ≤ 2000 mg/kg; Inhalation -vapor/gas – > 10 to ≤ 20mg/L/4hr; dust/mist/fume – > 1.0 to ≤ 5.0mg/L/4hr | Evidence of transient (1) irritant effects on respiratory tract in humans or (2) transient narcotic effects from animal studies and in humans | Adequate data available, and negative studies, no structural alerts, GHS not classified | |
| TOST – Repeat Exposure (Specific target organ systemic toxicity following repeated exposure; based on 90 day exposures) | GHS | GHS Category 1 | GHS Category 2 | Not Classified | |
| NOAEL/LOAEL oral (mg/kg/day): <10 | NOAEL/LOAEL oral (mg/kg/day): 10-100 | NOAEL/LOAEL oral (mg/kg/day): >100 | |||
| NOAEL/LOAEL dermal (mg/kg/day): <20 | NOAEL/LOAEL dermal (mg/kg/day): 20-200 | NOAEL/LOAEL dermal (mg/kg/day): >200 | |||
| NOAEL/LOAEL inhalation (vapor/gas) (mg/L/6h/day): <0.2 | NOAEL/LOAEL inhalation (vapor/gas) (mg/L/6h/day): 0.2-1.0 | NOAEL/LOAEL inhalation (vapor/gas) (mg/L/6h/day): >1.0 | |||
| NOAEL/LOAEL inhalation (dust/mist/fume) (mg/L/6h/day): <0.02 | NOAEL/LOAEL inhalation (dust/mist/fume) (mg/L/6h/day): 0.02-0.2 | NOAEL/LOAEL inhalation (dust/mist/fume) (mg/L/6h/day): >0.2 | |||
| Qualitative Assessment of Available Data including Modeling Alerts as needed | Reliable evidence of a significant adverse effect on specific organ/systems or systemic toxicity in humans or animals | Evidence of a harmful adverse effect on specific organ/systems or systemic toxicity from animal studies or humans. | Adequate data available, and negative studies, no structural alerts, GHS not classified. Modeling data may not be used alone. | ||
| Aspiration Hazard | GHS | GHS Category 1 | GHS Category 2 | ||
| Qualitative Assessment of Available Data | Human evidence; hydrocarbons with kinematic viscosity of 20.5 mm2/s or less, measured at 40° C | Based on animal studies; kinematic viscosity of 14 mm2/s or less, measured at 40°C | |||
| Dermal Sensitization | GHS | GHS Category 1A | GHS Category 1B | ||
| Substances showing a high frequency of occurrence in humans and/or a high potency in animals | Substances showing a low to moderate frequency of occurrence in humans and/or a low to moderate potency in animals | ||||
| Hazard Lists | MAK Sensitizing Substances Sh (Skin) or Sah (Respiratory and Skin) | ||||
| Qualitative Assessment of Available Data | Positive responses in predictive Human Repeat Insult Patch Tests (HRIPT) or other human experience or analogy to chemical classes and/or positive, animal or LLNA data. Modeling data may be used. | Modeling data may be used. | Adequate data available, and negative studies, no structural alerts, GHS not classified. Modeling data may not be used alone. | ||
| Respiratory Sensitization | GHS | GHS Category 1A | GHS Category 1B – Low to moderate sensitization rate in humans or probability thereof based upon animal or other tests | ||
| High sensitization rate in humans or probability thereof based upon animal or other tests | |||||
| Hazard Lists | MAK Sensitizing Substances Sa (Respiratory) or Sah (Respiratory and Skin) | AOEC | |||
| Neurotoxicity | See TOST, Single and Repeat | see TOST | see TOST | see TOST | |
| Hazard Lists | Listed on Grandjean & Landrigan (ME) | ||||
| Qualitative Assessment of Available Data | Evidence of neurotoxicity in humans or positive results in appropriate animal tests assessing functional observational battery, motor activity, neuropathology | Probable human neurotoxicant (some positive results in appropriate animal tests) | No evidence for a neurotoxic hazard |
Ecotox and E-Fate Endpoints
| Hazard | GHS+ Criteria | Very High | High | Moderate | Low |
| Eco Toxicity | |||||
| Acute Hazards to the Aquatic Environment | GHS | GHS Category 1 | GHS Category 2 | GHS Category 3 | GHS Category “Not Classified” |
| Qualitative Assessment of Available Data (modeling data may be used) | LC/EC50 ≤ 1mg/L (fish 96hr LC50, crustacea 48hr EC/LC50, or aquatic plant 72 or 96hr ErC50). | 1 mg/L < LC/EC50 ≤ 10 mg/L (fish 96hr LC50, crustacea 48hr EC/LC50, or aquatic plant 72 or 96hr ErC50) | 10 mg/L < LC/EC50 ≤ 100 mg/L (fish 96hr LC50, crustacea 48hr EC/LC50, or aquatic plant 72 or 96hr ErC50) | LC/EC50 > 100mg/L | |
| Chronic Hazards to the Aquatic Environment | GHS | GHS Category 1 | GHS Category 2 | GHS Category 3 and 4 | GHS Category “Not Classified” |
| Qualitative Assessment of Available Data (modeling data may be used) | LC/EC50 ≤ 0.1 mg/L | LC/EC50 > 0.1 to ≤ 1mg/L (fish 96hr LC50, crustacea 48hr EC/LC50, or aquatic plant 72 or 96hr ErC50) and BCF ≥ 500 or if absent log Kow ≥ 4 | > 1 mg/L 1mg/L. Category 4 – Poorly soluble and no acute toxicity is observed upon water solubility and BCF≥ 500 or if absent log Kow ≥ 4, unless chronic NOECs > 1mg/L | LC/EC50 >10 mg/L | |
| Environmental Fate | |||||
| Persistence | Qualitative Assessment of Available Data | ||||
| % Biodegradation in 28 days | ≤10% in 28 days, or when less than 30% in >28 days | greater than 10% to <30% in 28 days | ≥30% to 70% in 28 days | Rapidly degradable; Degradation >70% of dissolved organic carbon in 28 days (reached within a 10-day window); if not available BOD (5 days)/ COD ratio ≥0.5, considered indicative of rapid degradation | |
| Biological Oxygen Demand (BOD)/Chemical Oxygen Demand (COD) ratio | BOD (5 day)/COD ratio <0.2, not biodegradable | BOD (5 day)/COD ratio 0.2-0.4, slowly biodegradable | BOD (5 day)/COD ratio >0.4-0.5, moderately biodegradable | BOD (5 day)/COD ratio >0.5, easily biodegradable | |
| t 1/2 in days | Persistence in soil or sediment: Half-life>180 days or recalcitrant; Persistence in water: Half-life>60 days or recalcitrant; Persistence in air: >5 days or recalcitrant | Soil or Sediment: >60 to 180 days; Water: >40 to 60 days; Air 2 to 5 days | Soil or Sediment: 16 to 60 days; Water: 16 to 40 days; Air: Half-life assessed as high or low | Soil, Sediment, or Water<16 days; Air<2 days; GHS "Rapid degradability"; Meets 10-day "Ready Biodegradability" | |
| Chemical Class | Inorganic – Determined by compound characteristics under environmental conditions | ||||
| Potential for Long-range Transport | Evidence | Suggestive Evidence | |||
| Potential for Actual Bioaccumulation | Qualitative Assessment of Available Data (modeling data may be used) | BCF or BAF >5000 or log Kow >5 | BCF or BAF >1000 to 5000 or log Kow 4.5-5 | BCF or BAF 500 to 1000 or log Kow 4-4.5 | BCF or BAF >100 – 500 or log Kow <4.5 |
| Environmental Transformation Products (ETPs) | |||||
| Environmental Transformation Products (ETPs) | Qualitative Assessment of Available Data (modeling data may be used) | Experimental data indicating persistent and very highly toxic degradation products. | Experimental or modeling data indicating persistent and highly toxic degradation products. | Experimental or modeling data indicating persistent and moderately toxic degradation products. | Data are available suggesting low concern for ETPs (e.g., low persistence, low toxicity). |
| Mobility | |||||
| Mobility | Qualitative Assessment of Available Data (modeling data may be used) | Log Koc < 2.0 | 2.0 < Log Koc < 3.0 | Log Ko > 3.0 | |
Physical Hazard Endpoints
| Hazard | GHS+ Criteria | Very High | High | Moderate | Low |
| Flammability | GHS: Flammable Liquids | GHS Category 1 | GHS Category 2 | GHS Category 3 and 4 | GHS Category “Not Classified” |
| GHS: Flammable Gases | GHS Category 1 | GHS Category 2 or GHS Category A | GHS Category B or GHS Category “Not Classified” | ||
| GHS: Flammable Solids | GHS Category 1 | GHS Category 1 | GHS Category 2 | GHS Category 3 or GHS Category “Not Classified” | |
| GHS: Aerosols | LC/EC50 ≤ 0.1 mg/L | GHS Category 1 | GHS Category 2 | GHS Category 3 or GHS Category “Not Classified” | |
| GHS: Pyrophoric Liquids | GHS Category 1 | GHS Category “Not Classified” | |||
| GHS: Pyrophoric Solids | GHS Category 1 | GHS Category “Not Classified” | |||
| Qualitative Assessment of Available Data (modeling data may be used) | Flashpoint: flammable liquids | Flash point < 23 ∘C and initial boiling point ≤ 35 ∘C | Flash point < 23 ∘C and initial boiling point > 35 ∘C | Flash point ≥ 23 ∘C and ≤ 93 ∘C | Flash point > 93 ∘C |
| Reactivity | GHS: Explosives | GHS Unstable | GHS Division 1.1, 1.2, or 1.3 | GHS Division 1.4 or 1.5 | GHS Division 1.6 or GHS Category “Not Classified” |
| GHS: Self-reactive Substances | GHS Type A or B | GHS Type C or D | GHS Type E or F | GHS Type G or GHS Category “Not Classified” | |
| GHS: Substances which on contact with water emit flammable gases | GHS Category 1 | GHS Category 2 | GHS Category 3 | GHS Category “Not Classified” | |
| GHS: Oxidizing Gases | GHS Type A or B | GHS Type C or D | GHS Type E or F | GHS Type G or GHS Category “Not Classified” | |
| GHS: Oxidizing Liquids and Solids | GHS Category 1 | GHS Category 2 | GHS Category 3 | GHS Category “Not Classified” | |
| GHS: Organic Peroxides | GHS Type A or B | GHS Type C or D | GHS Type E or F | GHS Type G or GHS Category “Not Classified” | |
| GHS: Self-Heating Substances | Experimental data indicating persistent and very highly toxic degradation products. | GHS Category 1 | GHS Category 2 | GHS Category “Not Classified” | |
| GHS: Substances Corrosive to Metal | GHS Category 1 | GHS Category “Not Classified” |
Appendix B: List Screening in SciveraLENS®: Roster of Lists Available
The Enhesa team manages and maintains over 600 lists and sub lists and makes these available to SciveraLENS subscribers for instant screening. Our Toxicologists review hundreds of globally recognized lists that are created by regulatory agencies, organizations, NGOs, etc. We add the lists that matter most to our customers into SciveraLENS so that you can quickly see if any of your chemicals appear on a list of interest. In addition to monitoring these lists and making sure that you always have the most complete and up-to-date list when screening your chemicals, our Toxicologists also expand any lists that include chemical groups or families. This means that we identify all CAS numbers associated with a chemical group or family so that you get the most complete and accurate screening results. If anything changes on a list that you’re tracking, you’ll receive real-time alerts letting you know of the change.
Our lists are separated into 8 different Types:
- Authoritative: Authoritative lists come from recognized experts that identify known hazards and are considered reliable and high confidence sources.
- Examples include: IARC – Cancer Monographs Carcinogen Groups, NTP-OHAT Lists
- Chemical Group: A chemical group refers to a classification of chemicals that share similar structural characteristics, functional groups, or properties. These groups are often used to organize substances for hazard assessment, regulatory purposes, or scientific study. Examples include halogens, phthalates, polycyclic aromatic hydrocarbons (PAHs), or per- and polyfluoroalkyl substances (PFAS). Grouping chemicals helps streamline evaluations by identifying shared risks, behaviors, or environmental impacts within the group.
- Examples include Aluminum, PFAS, Flame Retardants
- Informational or Inventory List: Informational or Inventory Lists catalog chemicals for reference purposes, offering details such as chemical names, structures, uses, and properties. They are not tied to regulatory or compliance requirements but serve as a resource for stakeholders to understand chemical characteristics or track inventory.
- Examples include: Canada DSL, The International Fragrance Association (IFRA) Transparency List
- Preferred List: Preferred lists identify chemicals or materials that meet specific safety, environmental, or performance criteria, making them favorable for use. These lists are often developed to promote safer and more sustainable alternatives in product design and manufacturing.
- Examples include: EPA Safer Chemical Ingredient List, ChemForward Safer Flame Retardants List
- Regulatory List: Regulatory lists are developed and maintained by government agencies or authoritative bodies to identify substances that are subject to legal or compliance requirements. These lists are enforceable and often specify restrictions, bans, or reporting obligations, ensuring adherence to regional or international laws.
- Examples include: California Proposition 65, ECHA, EU REACH, Oregon Health Authority, Washington State CHCC
- Restricted Substance List: Restricted Substance Lists (RSLs) identify chemicals that are limited or prohibited in specific products, industries, or regions. Typically developed by companies, industry groups, or organizations, these lists are designed to ensure compliance with regulatory requirements, align with sustainability goals, or meet customer demands.
- Examples include: Cradle to Cradle lists, Specific brand RSLs
- Screening List: Screening lists flag chemicals for preliminary assessment based on hazard, exposure, or regulatory status. They help prioritize substances for further evaluation or management, often serving as an initial step in risk assessment processes.
- Examples include: AOEC Asthmagens, Grandjean & Landrigan Neurotoxic Chemicals, Silent Spring Institute Mammary Carcinogens Reviews Database
- Watch List: Watch lists identify chemicals of emerging concern that may pose potential risks to health or the environment. While not yet subject to regulatory action, these substances are monitored closely for new scientific data or regulatory developments, enabling proactive management.
- Examples include: European Commission Restrictions Roadmap Under the Chemical Strategy for Sustainability European Green Deal, Scientific Committee on Consumer Safety (SCCS), International Living Future Institute – Living Building Challenge Watch List
If you don’t see a list that you’re interested in, please let us know and we can work with you to add what you need.
Lists Managed in SciveraLENS (March 27, 2025)
Australia (AU) Government Department of Health and Aged Care (DHAC) Inventory of Industrial Chemicals (AIIC)
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Additional Category Reproductive Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Acute Dermal Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Acute Inhalation Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Acute Oral Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Aspiration Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Corrosive to Metals
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Eye Damage
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Flammable Gases
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Flammable Liquids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Flammable Solid
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Hazardous to the Aquatic Environment, Acute Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Hazardous to the Aquatic Environment, Long-Term Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Hazardous to the Ozone Layer
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Oxidizing Gases
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Oxidizing Liquids/Solids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Pyrophoric Liquids/Solids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Respiratory Sensitisation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Self-heating Substances and Mixture
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Skin Corrosion/Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Skin Sensitisation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Specific Target Organ Toxicity, Repeated Exposure
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Specific Target Organ Toxicity, Single Exposure
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1 Substances Which, in Contact with Water, Emit Flammable Gases
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1A Carcinogenicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1A Reproductive Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1A Skin Corrosion/Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1A Skin Sensitisation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1B Carcinogenicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1B Germ Cell Mutagenicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1B Reproductive Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1B Skin Corrosion/Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1B Skin Sensitisation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 1C Skin Corrosion/Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Acute Dermal Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Acute Inhalation Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Acute Oral Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Carcinogenicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Flammable Gases
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Flammable Liquids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Flammable Solid
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Germ Cell Mutagenicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Hazardous to the Aquatic Environment, Acute Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Hazardous to the Aquatic Environment, Long-Term Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Oxidizing Liquids/Solids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Reproductive Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Self-heating Substances and Mixture
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Skin Corrosion/Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Specific Target Organ Toxicity, Repeated Exposure
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Specific Target Organ Toxicity, Single Exposure
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2 Substances Which, in Contact with Water, Emit Flammable Gases
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 2A Eye Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Acute Dermal Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Acute Inhalation Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Acute Oral Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Flammable Liquids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Hazardous to the Aquatic Environment, Acute Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Hazardous to the Aquatic Environment, Long-Term Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Oxidizing Liquids/Solids
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Skin Corrosion/Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Specific Target Organ Toxicity, Single Exposure; Narcotic Effects
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 3 Specific Target Organ Toxicity, Single Exposure; Respiratory Tract Irritation
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 4 Acute Inhalation Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 4 Acute Oral Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 4 Acute Toxicity
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Category 4 Hazardous to the Aquatic Environment, Long-Term Hazard
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) H200 Explosives
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) H201 Explosives
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) H203 Explosives
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type A Organic Peroxides
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type A Self-reactive Substances and Mixtures
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type B Self-reactive Substances and Mixtures
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type C Organic Peroxides
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type C Self-reactive Substances and Mixtures
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type D Organic Peroxides
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type D Self-reactive Substances and Mixtures
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type E Organic Peroxides
Australia (AU) Safe Work Australia (SWA) GHS Classifications under the Work Health and Safety Act (WHS) Type F Organic Peroxides
Australia (AU) Safe Work Australia (SWA) Prohibited Carcinogens under the Work Health and Safety Act
Australia (AU) Safe Work Australia (SWA) Restricted Carcinogens under the Work Health and Safety Act
Australia (AU) Safe Work Australia (SWA) Restricted Hazardous Chemicals under the Work Health and Safety Act
Australia-GHS-Eye Damage/Irritation Category 2B
Australia-GHS-Organic Peroxides-Type B
Brazil (BR) National Health Surveillance Agency (ANVISA) Permitted Preservative Substances for Personal Care Products, Cosmetics, and Perfumes RDC 528/2021
Brazil (BR) National Health Surveillance Agency (ANVISA) Prohibited Substances for Manufacturers and Importers of Personal Care Products, Cosmetics, and Perfumes RDC 529/2021
Canada (CA) Canadian Food Inspection Agency (CFIA) Plant and Animal Health Strategy, List of Prescribed Deleterious Substances
Canada (CA) Environment and Climate Change Canada (ECCC) Canadian Environmental Protection Act (CEPA) Environmental Registry Toxic Substances List (Schedule 1)
Canada (CA) Environment and Climate Change Canada (ECCC) Canadian Environmental Protection Act 1999 Notice With Request to Certain Per- Polyfluoroalkyl Substances (PFAS)
Canada (CA) Environment and Climate Change Canada (ECCC) Canadian Environmental Protection Act Virtual Elimination List (CEPA)
Canada (CA) Environment and Climate Change Canada (ECCC) Domestic Substances List (DSL) Results for all Existing Substances
Canada (CA) Environment and Climate Change Canada (ECCC) Domestic Substances List (DSL) Substances that meet human health categorization criteria
Canada (CA) Environment and Climate Change Canada (ECCC) Domestic Substances List Substances that are Persistent, Bioaccumulative and Inherently Toxic to the environment (PBiT)
Canada (CA) Environment and Climate Change Canada (ECCC) Environmental Emergency Regulations (SOR/2019-51 Part1)
Canada (CA) Environment and Climate Change Canada (ECCC) Environmental Emergency Regulations (SOR/2019-51 Part2)
Canada (CA) Health Canada (HC) Consumer Chemicals and Containers Regulations Substances of Special Concern
Canada (CA) Health Canada (HC) Cosmetic Ingredient Hotlist Prohibited
Canada (CA) Health Canada (HC) Cosmetic Ingredient Hotlist Restricted
Canada (CA) Health Canada (HC) Quebec Workplace Hazardous Materials Information System (WHMIS)
Chile (CL) Ministry of Health of Chile Managing Airborne Hazardous Substance Exposure in the Workplace (Decree 594 Article 61)
Chile (CL) Ministry of the Environment (MMA) National Chemical Substances Inventory
China (CN) Chongqing Municipal People’s Government (CQMPG) Catalogue of Controlled Hazardous Chemicals
China (CN) Chongqing Municipal People’s Government (CQMPG) Catalogue of Prohibited Hazardous Chemicals
China (CN) Chongqing Municipal People’s Government (CQMPG) Catalogue of Restricted Hazardous Chemicals
China (CN) Ministry of Ecology and Environment of the People’s Republic of China (MEE) Inventory of Existing Chemical Substances
China (CN) Ministry of Ecology and Environment of the People’s Republic of China (MEE) List of Controlled Ozone Depleting Substances
China (CN) Ministry of Ecology and Environment of the People’s Republic of China (MEE) The List of Chemicals for Prioritized Control
China (CN) Ministry of Ecology and Environment of the People’s Republic of China (MEE) The List of Key Controlled New Pollutants
China (CN) Ministry of Emergency Management of the People’s Republic of China (MEM) Catalogue of Hazardous Chemicals
China (CN) Ministry of Emergency Management of the People’s Republic of China (MEM) Catalogue of Specially Controlled Hazardous Chemicals
China (CN) Ministry of Industry and Information Technology of the People’s Republic of China (MIIT) Restriction of Hazardous Substances in Electronic and Electrical Equipment (China RoHS)
Denmark (DK) Danish Environmental Protection Agency (DEPA) List of Undesirable Substances
European Union (EU) European Chemicals Agency (ECHA) Article 95 of the Biocidal Products Regulation (BPR) List
European Union (EU) European Chemicals Agency (ECHA) Batteries and Waste Batteries Prohibitions and Labelling Regulation (EU) 2023/1542 Annexes I and VI
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Acute Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Aquatic Acute
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Aquatic Chronic
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Aspiration Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Eye Damage
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Respiratory Sensitization
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 STOT Repeat Exposure
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 STOT Single Exposure
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Skin Corrosion
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1 Skin Sensitization
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1A Carcinogenicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1A Mutagenicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1A Reproductive Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1A Skin Corrosion
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1A Skin Sensitization
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1B Carcinogenicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1B Mutagenicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1B Reproductive Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1B Skin Corrosion
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1B Skin Sensitization
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 1C Skin Corrosion
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Acute Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Aquatic Acute
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Aquatic Chronic
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Carcinogenicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Eye Irritation
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Mutagenicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Reproductive Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 STOT Repeat Exposure
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 STOT Single Exposure
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 2 Skin Irritation
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 3 Acute Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 3 Aquatic Chronic
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 3 STOT Single Exposure
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 4 Acute Toxicity
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Category 4 Aquatic Chronic
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging (CLP Regulation) Lactation
European Union (EU) European Chemicals Agency (ECHA) Classification, Labelling and Packaging of Substances and Mixtures (CLP) All Health, Environmental, Physical Harmonized Classifications
European Union (EU) European Chemicals Agency (ECHA) Co-formulants not Accepted for Inclusion in Plant Protection Products (PPP) Regulation 1107/2009/EC Annex III
European Union (EU) European Chemicals Agency (ECHA) Endocrine disruptor assessment list Environmental Health
European Union (EU) European Chemicals Agency (ECHA) Endocrine disruptor assessment list Full
European Union (EU) European Chemicals Agency (ECHA) Endocrine disruptor assessment list Human Health
European Union (EU) European Chemicals Agency (ECHA) Endocrine disruptor assessment list Not Endocrine Disrupting
European Union (EU) European Chemicals Agency (ECHA) Flame Retardant Strategy List
European Union (EU) European Chemicals Agency (ECHA) PBT/vPvB assessments under the previous EU chemicals legislation
European Union (EU) European Chemicals Agency (ECHA) Persistent Organic Pollutants (POPs) Regulation (EU) 2019/1021 (Including Annexes I, II, III, IV)
European Union (EU) European Chemicals Agency (ECHA) Prior Informed Consent (PIC) Regulation Annex I
European Union (EU) European Chemicals Agency (ECHA) Proposed REACH Restricted Dermal Sensitizers
European Union (EU) European Chemicals Agency (ECHA) REACH Annex XIV SVHC Authorisation list
European Union (EU) European Chemicals Agency (ECHA) REACH Annex XVII Substances restricted under REACH
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Carcinogenic (Article 57a)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Endocrine disrupting properties (Article 57(f) – environment)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Endocrine disrupting properties (Article 57(f) – human health)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Equivalent level of concern having probable serious effects to human health (Article 57f)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Equivalent level of concern having probable serious effects to the environment (Article 57f)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Mutagenic (Article 57b)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List PBT (Article 57d)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Respiratory sensitising properties (Article 57(f) – human health)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Specific target organ toxicity after repeated exposure (Article 57(f) – human health)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List Toxic for reproduction (Article 57c)
European Union (EU) European Chemicals Agency (ECHA) REACH Substances of High Concern (EU SVHC) Candidate List vPvB (Article 57e)
European Union (EU) European Chemicals Agency (ECHA) Recommended chemicals for EU REACH Annex XIV SVHC Authorisation list
European Union (EU) European Chemicals Agency (ECHA) Registry of SVHC intentions until outcome-Intentions
European Union (EU) European Chemicals Agency (ECHA) Submitted SVHC Intentions-Full
European Union (EU) European Commission (EC) Conflict Minerals Regulation
European Union (EU) European Commission (EC) Cosmetics Ingredients: Annex III List of Substances Restricted in Cosmetic Products
European Union (EU) European Commission (EC) Cosmetics Ingredients: Annex IV List of Colorants Allowed in Cosmetic Products
European Union (EU) European Commission (EC) Cosmetics Ingredients: Annex V List of Preservatives Allowed in Cosmetic Products
European Union (EU) European Commission (EC) Cosmetics Ingredients: Annex VI List of UV Filters Allowed in Cosmetic Products
European Union (EU) European Commission (EC) EU Ecolabel Restricted Substances List for Footwear
European Union (EU) European Commission (EC) EU Ecolabel Restricted Substances List for Textile Products
European Union (EU) European Commission (EC) Ecodesign Requirements for Electronic Displays Commission Regulation (EU) 2019/2021 Annex II
European Union (EU) European Commission (EC) List of Prohibited Fragrance Ingredients under Annex II Regulation 1223/2009/EC
European Union (EU) European Commission (EC) List of Prohibited Substances in All Cosmetic Products under Annex II Regulation 1223/2009/EC
European Union (EU) European Commission (EC) List of Prohibited Substances in Hair Dye Products under Annex II Regulation 1223/2009/EC
European Union (EU) European Commission (EC) Ozone depletion substances (ODS)
European Union (EU) European Commission (EC) Pollutant Release and Transfer Register Regulation (EC) No 166/2006 Annex II Pollutants
European Union (EU) European Commission (EC) Priority Substances Directive (Directive 2008/105/EC Annex II)
European Union (EU) European Commission (EC) Prohibition of Mercury and Mercury Containing Products (Regulation 2017/852)
European Union (EU) European Commission (EC) Restriction of Hazardous Substances Directive (RoHS) Restricted Substances
European Union (EU) European Commission (EC) Restrictions Roadmap Under the Chemical Strategy for Sustainability Pool 0 European Green Deal
European Union (EU) European Commission (EC) Restrictions Roadmap Under the Chemical Strategy for Sustainability Pool 1 European Green Deal
European Union (EU) European Commission (EC) Restrictions Roadmap Under the Chemical Strategy for Sustainability Pool 2 European Green Deal
European Union (EU) European Commission (EC) SEVESO-III Directive on the Control of Major Accident Hazards Involving Dangerous Substances Annex I Part 2
European Union (EU) European Commission (EC) Toy Safety Directive 2009/48/EC Allergenic Fragrances (Banned List)
European Union (EU) European Commission (EC) Toy Safety Directive 2009/48/EC Allergenic Fragrances (Labeling List)
European Union (EU) European Commission (EC) Toy Safety Directive 2009/48/EC EN 71-3 Safety of toys Annex II Migration Limits on Metal
European Union (EU) European Commission (EC) Waste from Electrical and Electronic Equipment WEEE Directive (Annex VII)
European Union (EU) European Food Safety Authority (EFSA) Union List of Authorised Substances for Food Contact Materials
European Union (EU) National Competent Authorities (NCAs) List of Substances Considered as Endocrine Disruptors – List III
European Union (EU) National Competent Authorities (NCAs) Substances Identified as Endocrine Disruptors at EU Level – List I
European Union (EU) National Competent Authorities (NCAs) Substances under Evaluation for Endocrine Disruption in EU Legislation – List II
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Final Opinions
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Fragrance Allergens Established contact allergens in humans
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Fragrance Allergens Established fragrance contact allergens of special concern (single chemicals only)
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Fragrance Allergens Fragrance substances categorised as established contact allergens in animals
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Fragrance Allergens Fragrance substances categorised as likely contact allergens by combination of evidence
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Fragrance Allergens Fragrance substances categorised as possible contact allergens
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Opinions being finalised
European Union (EU) Scientific Committee on Consumer Safety (SCCS) Preliminary Opinions open for comments
Germany (DE) Federal Environment Agency (UBA) Class 0 Substances, Non-Hazardous to Water
Germany (DE) Federal Environment Agency (UBA) Class 1 Substances, Low Hazard to Water
Germany (DE) Federal Environment Agency (UBA) Class 2 Substances, Hazardous to Water
Germany (DE) Federal Environment Agency (UBA) Class 3 Substances, Severely Hazardous to Water
Germany (DE) Federal Environment Agency (UBA) Substances Generally Hazardous to Water (AWG)
Germany (DE) German Research Foundation (DFG) List of Substances in the MAK Classification for Germ Cell Mutagenicity
Germany (DE) German Research Foundation (DFG) List of Substances in the MAK Classification for Pregnancy Risk Group
Germany BAT Carcinogenic Substances Categories 1
Germany BAT Carcinogenic Substances Categories 2
Germany MAK Carcinogenic Substances Categories 1
Germany MAK Carcinogenic Substances Categories 2
Germany MAK Carcinogenic Substances Categories 4
Germany MAK Carcinogenic Substances Categories 5
Germany MAK Carcinogenic Substances Category 3
Germany MAK Sensitizing Substances
Indonesia (ID) National Agency of Drug and Food Control of Indonesia (BPOM) Appendix V, Not Permitted Chemicals in Cosmetics
Indonesia (ID) National Agency of Drug and Food Control of Indonesia (BPOM) Food and Drug Administration Appendix I, Permitted Cosmetic Ingredients
Indonesia (ID) National Agency of Drug and Food Control of Indonesia (BPOM) Food and Drug Administration Appendix II, Colouring Agents Permitted in Cosmetics
Indonesia (ID) National Agency of Drug and Food Control of Indonesia (BPOM) Food and Drug Administration Appendix III, Preservatives Permitted in Cosmetics
Indonesia (ID) National Agency of Drug and Food Control of Indonesia (BPOM) Food and Drug Administration Appendix IV, Sunscreen Ingredients Permitted in Cosmetics
International (XE) Acer Restricted Substances
International (XE) Adidas Policy for the Control and Monitoring of Hazardous Substances
International (XE) Amazon AWS
International (XE) Amazon Devices RSL
International (XE) Amazon Private Brands
International (XE) Amazon Robotics Additional Chemicals
International (XE) Amazon Robotics Packaging Content Labelling (State-Level Regulations)
International (XE) American Apparel & Footwear Association (AAFA) Restricted Substance List
International (XE) Apparel and Footwear International RSL Management Group (AFIRM Group) Packaging Restricted Substances List
International (XE) Apparel and Footwear International RSL Management Group (AFIRM Group) Restricted Substance List
International (XE) Apple Regulated Substances Specification 069-0135-M Reportable Substances and Future Restriction in Products
International (XE) Apple Regulated Substances Specification 069-0135-M Restricted Substances in Products
International (XE) BlueSign Restricted Substance List
International (XE) C&A Restricted Substance List (C&A specific requirements. See description to select additional lists)
International (XE) ChemForward Safer Flame Retardants List
International (XE) Clean Electronics Production Network (CEPN) Priority Chemicals List
International (XE) Clean Production Action Chemical Footprint Project (CFP) Chemicals of High Concern (CoHCs) Reference List v3.0
International (XE) Clean Production Action Standard for Food Service Ware
International (XE) Conference of the Parties (COP) Stockholm Convention on Persistent Organic Pollutants (POPs)
International (XE) Cradle to Cradle (C2C) V4.1 Additional Restrictions for Biological and Environmentally Released Materials
International (XE) Cradle to Cradle (C2C) V4.1 Additional Restrictions for Children’s Products
International (XE) Cradle to Cradle (C2C) V4.1 Additional Restrictions for Cosmetics and Personal Care Products
International (XE) Cradle to Cradle (C2C) V4.1 Additional Restrictions for Footwear, Apparel, and Jewelry Products
International (XE) Cradle to Cradle (C2C) V4.1 Additional Restrictions for Formulated Consumer Products
International (XE) Cradle to Cradle (C2C) V4.1 Additional Restrictions for Textile Materials
International (XE) Credo Beauty Restricted Substance List
International (XE) Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers (ETAD) Heavy Metal Limits Included in Annex 2 for Dyes Under Zero Discharge of Hazardous Chemicals – ZDHC Sublist
International (XE) Enhesa Alkylphenols and Alkylphenol Ethoxylates (APEs)
International (XE) Enhesa Aluminum
International (XE) Enhesa Antimony
International (XE) Enhesa Arsenic
International (XE) Enhesa Barium
International (XE) Enhesa Bisphenol A (BPA) Based Chemistries and Related Compounds
International (XE) Enhesa Borates
International (XE) Enhesa Brominated and Chlorinated Flame Retardants
International (XE) Enhesa Cadmium
International (XE) Enhesa Chromium
International (XE) Enhesa Cobalt
International (XE) Enhesa Copper
International (XE) Enhesa Flame Retardants
International (XE) Enhesa Fluorinated Greenhouse Gases
International (XE) Enhesa Halogenated Diarylalkanes
International (XE) Enhesa Heavy Metals
International (XE) Enhesa Lead
International (XE) Enhesa Mercury
International (XE) Enhesa Nickel
International (XE) Enhesa Nonylphenol and ethoxylates
International (XE) Enhesa Octylphenols and ethoxylates
International (XE) Enhesa PFOA and salts and esters
International (XE) Enhesa Parabens
International (XE) Enhesa Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS)
International (XE) Enhesa Perfluorooctane Sulfonate (PFOS) and related compounds
International (XE) Enhesa Phthalates
International (XE) Enhesa Polybrominated Diphenyl Ethers (PBDEs)
International (XE) Enhesa Polychlorinated Biphenyls
International (XE) Enhesa Polychlorinated Naphthalenes
International (XE) Enhesa Polychorinated Terphenyls
International (XE) Enhesa Polycyclic Aromatic Hydrocarbons
International (XE) Enhesa Selenium
International (XE) Enhesa Tin
International (XE) Enhesa Tin Organic
International (XE) Enhesa UV Stabilizers and Absorbers
International (XE) Enhesa Volatile Organic Compounds (VOCs)
International (XE) Environmental Defense Fund (EDF) Packaging Restricted Substance List
International (XE) Food Packaging Forum (FPF) Food Contact Chemicals database (FCCdb) V 5.0
International (XE) Food Packaging Forum (FPF) Food Contact Chemicals database V 5.0 Priority Substances List
International (XE) Global Automotive Declarable Substance List (GADSL) Declarable Substances
International (XE) Global Automotive Declarable Substance List (GADSL) Declarable/Prohibited Substances
International (XE) Global Automotive Declarable Substance List (GADSL) Prohibited Substances
International (XE) Global Organic Textile Standard (GOTS) Manual for the implementation of GOTS v7.1
International (XE) Green Science Policy Institute (GSPI) Six Classes Antimicrobials
International (XE) Green Science Policy Institute (GSPI) Six Classes Bisphenols and Phthalates
International (XE) Green Science Policy Institute (GSPI) Six Classes Certain Metals
International (XE) Green Science Policy Institute (GSPI) Six Classes Flame Retardants
International (XE) Green Science Policy Institute (GSPI) Six Classes PFAS
International (XE) Green Science Policy Institute (GSPI) Six Classes Some Solvents
International (XE) Greenpeace’s Global Research on Potentially Hazardous Chemicals – GreenPeace 11 Full
International (XE) H&M Group Chemical Restrictions Additional Requirements MRSL and RSL
International (XE) H&M MRSL Combined Groups 1 and 2
International (XE) H&M MRSL Group 1
International (XE) H&M MRSL Group 2
International (XE) H&M RSL Aerosol Dispensers
International (XE) H&M RSL Apparel Accessories Footwear Home Interior Textile Products
International (XE) H&M RSL Candles
International (XE) H&M RSL Chemical Products
International (XE) H&M RSL Combined
International (XE) H&M RSL Cosmetic Products
International (XE) H&M RSL Electrical and Electronic Products and Batteries
International (XE) H&M RSL Food Contact Products
International (XE) H&M RSL Hardline
International (XE) H&M RSL Medical devices
International (XE) H&M RSL Packaging
International (XE) H&M RSL Toys
International (XE) Healthier Hospitals Initiatives (HHI) Safer Chemicals Healthy Interiors Guidance
International (XE) Healthy Building Network Priority Asthmagens
International (XE) International Aerospace Environmental Group (IAEG) Aerospace and Defense Declarable Substances List
International (XE) International Agency for Research on Cancer (IARC) Cancer Monographs Carcinogens Group 1
International (XE) International Agency for Research on Cancer (IARC) Cancer Monographs Carcinogens Group 2A
International (XE) International Agency for Research on Cancer (IARC) Cancer Monographs Carcinogens Group 2B
International (XE) International Agency for Research on Cancer (IARC) Cancer Monographs Carcinogens Group 3 “not classifiable as to its carcinogenicity to humans”
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) All Chemicals by CAS RN (Not Enhea Expanded)
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) All Chemicals with 15 Chemical Groups
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) Carcinogenicity Health Concern
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) Endocrine Activity Health Concern
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) Mutagenicity Health Concern
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) PBT
International (XE) International Chemical Secretariat (ChemSec) Substitute it Now List (SIN) Toxic to Reproduction
International (XE) International Chemical Secretariat (ChemSec) The 32 to leave behind, high concern endocrine disrupting chemicals
International (XE) International Fragrance Association (IFRA) Standards Prohibited Substances
International (XE) International Fragrance Association (IFRA) Standards Restricted and Specified Substances
International (XE) International Living Future Institute (ILFI) Living Building Challenge Watch List
International (XE) International Living Future Institute (ILFI) Living Building Challenge Watch List (Not Enhesa Expanded)
International (XE) International Living Future Institute (ILFI) Living Building Challenge Watch List: Priority for Red List Inclusion
International (XE) International Living Future Institute (ILFI) Living Building Challenge Watch List: Priority for Red List Inclusion (Not Enhesa Expanded)
International (XE) International Living Future Institute Living Building Red List
International (XE) International Living Future Institute Living Building Red List (Enhesa Enhanced)
International (XE) International Panel on Chemical Pollution (IPCP) San Antonio Statement on Brominated and Chlorinated Flame Retardants
International (XE) Lancet Grandjean & Landrigan Neurotoxic Chemicals
International (XE) Levi S & Co RSLUsage Banned
International (XE) Levi Strauss & Co. (Levi’s) Product Safety by Design Framework for Restricted Substances List
International (XE) Mind the Store The Ban the Bad Priority List
International (XE) NextGen Integrated RSL for Food Packaging Materials
International (XE) Nike Electronics RSL Full
International (XE) Nike List Hazardous Air Pollutants
International (XE) Nike List Volatile Organic Compounds
International (XE) Nike Packaging Restricted Substances List
International (XE) Nike Priority Chemicals for Formulation Cap
International (XE) Nike Restricted Substance List for Toys
International (XE) Nike Restricted Substances List Chemical Group Volatile Organic Compounds (VOCs)
International (XE) Nike Restricted Substances List Core CAS RNs
International (XE) OEKO-TEX Eco Passport Standard for Chemical Products Used in the Textile, Leather and Clothing Industries – Annex 6
International (XE) Organisation for Economic Co-operation and Development (OECD) Per- and Polyfluoroalkyl Substances (PFAS)
International (XE) Oslo and Paris Conventions for the Protection of the Marine Environment (OSPAR) Chemicals for Priority Action Part A
International (XE) Oslo and Paris Conventions for the Protection of the Marine Environment (OSPAR) Commission Substances of Possible Concern
International (XE) Oslo and Paris Conventions for the Protection of the Marine Environment (OSPAR) Priority Action List
International (XE) Packaging Pilot Base RSL
International (XE) Patagonia Restricted Substances List
International (XE) Pattys Toxicology Boyes Neurotoxicants 2001
International (XE) Perkins + Will Architects Precautionary List
International (XE) Perkins + Will Architects Watch List
International (XE) SC Johnson (SCJ) Potential Skin Allergens
International (XE) Safer Chemicals Healthy Families The Hazardous 100+ List of Chemicals of High Concern
International (XE) Sephora Global Clean at Sephora Formula Banned List EU
International (XE) Sephora Public Chemicals Policy High-Priority Chemicals
International (XE) Silent Spring Institute Mammary Carcinogens Reviews Database
International (XE) Standard 100 by OEKO-TEX Appendix 5 individual substances for Appendix 4
International (XE) Sustainable Textile & Leather Production (STeP) by OEKO-TEX
International (XE) The Endocrine Disruption Exchange (TEDX) Potential Endocrine Disruptors
International (XE) The International Fragrance Association (IFRA) Transparency List
International (XE) Toxics in Packaging Clearinghouse (TPCH) Restricted Substances List
International (XE) United Nations Environment Programme (UNEP) Rotterdam Convention Prior Informed Consent (PIC) Annex III Chemicals
International (XE) United Nations Environment Programme (UNEP) The Montreal Protocol on Ozone-Depleting Substances (Including All Annexes)
International (XE) Walmart High Priority Chemicals
International (XE) World Health Organization (WHO) Active Ingredients Believed to Be Obsolete or Discontinued for Use as Pesticides
International (XE) World Health Organization (WHO) Extremely Hazardous Pesticide Active Ingredients – Class Ia
International (XE) World Health Organization (WHO) Gaseous or Volatile Fumigants Not Classified in the WHO Recommended Classification of Pesticides
International (XE) World Health Organization (WHO) Highly Hazardous Pesticide Active Ingredients – Class Ib
International (XE) World Health Organization (WHO) Moderately Hazardous Pesticide Active Ingredients – Class II
International (XE) World Health Organization (WHO) Pesticide Active Ingredients Unlikely to Present Acute Hazard in Normal Use
International (XE) World Health Organization (WHO) Slightly Hazardous Pesticide Active Ingredients – Class III
International (XE) Zero Discharge of Hazardous Chemicals (ZDHC) MRSLV3.1 Chapter 1 Textile, Leather, and Polymers (CASRNs + Groups)
International (XE) Zero Discharge of Hazardous Chemicals (ZDHC) MRSLV3.1 Chapter 2 Candidate List (CASRNs + Groups)
International (XE) Zero Discharge of Hazardous Chemicals (ZDHC) MRSLV3.1 Chapter 3 Archived List
International WELL Building Institute (IWBI) Building Materials Disallowed by the WELL Building Standard (Enhesa Expanded)
Japan (JP) Electronics and Information Technology Industries Association (JEITA) Industrial Standards for Specific Chemicals in Electrical and Electronic Equipment (Japanese RoHS, also known as J-Moss)
Japan (JP) Japan Society for Occupational Health (JSOH) List of Occupational Carcinogens
Japan (JP) Japan Society for Occupational Health (JSOH) List of Occupational Sensitizers
Japan (JP) Japan Society for Occupational Health (JSOH) List of Reproductive Toxicants
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Act on the Control of Household Products Containing Harmful Substances
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Carcinogenic Substances Category 1A under the Industrial Safety and Health Act (ISHA)
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Carcinogenic Substances Category 1B under the Industrial Safety and Health Act (ISHA)
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Chemical Substances Causing Skin Disorders under the Industrial Safety and Health Act (ISHA)
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Highly Mutagenic Substances under the Industrial Safety and Health Act (ISHA)
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Poisonous and Deleterious Substances Control Act
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Positive List of Additives in Food Apparatus, Containers, and Packaging – Table 2
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Securing the Quality, Efficacy, and Safety of Cosmetic Products under Pharmaceuticals and Medical Devices Act
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Substances Excluded from Organic Cyanide Compounds under the Poisonous and Deleterious Substances Control Act
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) Substances Subject to Risk Assessment under the Industrial Safety and Health Act (ISHA)
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Acute Oral Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Aspiration
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Carcinogenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Dermal Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Dermal Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Flammable Liquids
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Reproductive Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Respiratory Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Serious Eye Damage/Eye Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1A Carcinogenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1A Dermal Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1A Reproductive Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1A Respiratory Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1A-1B Carcinogenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1B Carcinogenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1B Dermal Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1B Germ Cell Mutagenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1B Reproductive Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1B Respiratory Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Acute Inhalation Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Acute Oral Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Aspiration
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Carcinogenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Dermal Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Flammable Liquids
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Germ Cell Mutagenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Reproductive Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2 Serious Eye Damage/Eye Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2A Serious Eye Damage/Eye Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2A-2B Serious Eye Damage/Eye Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 2B Serious Eye Damage/Eye Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 3 Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 3 Acute Inhalation Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 3 Acute Oral Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 3 Dermal Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 4 Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 4 Acute Inhalation Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 4 Acute Oral Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 5 Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 5 Acute Inhalation Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 5 Acute Oral Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Acute Inhalation Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Acute Oral Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Carcinogenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Dermal Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Germ Cell Mutagenicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Reproductive Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Respiratory Sensitization
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Not Classified Serious Eye Damage/Eye Irritation
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) – Full
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Acute Dermal Toxicity
Japan (JP) Ministry of Health, Labour and Welfare (MHLW) The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 Acute Inhalation Toxicity
Japan (JP) Ministry of the Environment (MOEJ) Chemical Substances Control Law (CSCL) Class I Specified Chemical Substances
Japan (JP) Ministry of the Environment (MOEJ) Chemical Substances Control Law (CSCL) Class II Specified Chemical Substances
Japan (JP) Ministry of the Environment (MOEJ) Chemical Substances Control Law (CSCL) Monitoring Chemical Substances
Japan (JP) Ministry of the Environment (MOEJ) Chemical Substances Control Law (CSCL) Priority Assessment Chemical Substances (PACSs)
Japan (JP) Ministry of the Environment (MOEJ) Pollutant Release and Transfer Register Law (PRTR Act – Class Ⅰ specific substances)
Japan (JP) Ministry of the Environment (MOEJ) Pollutant Release and Transfer Register Law (PRTR Act – Class Ⅰ)
Japan (JP) Ministry of the Environment (MOEJ) Pollutant Release and Transfer Register Law (PRTR Act – Class ⅠⅠ)
Japan (JP) Ministry of the Environment (MOEJ) Water Pollution Prevention Act
Korea (KR) Ministry of Environment (MOE) Designation of Restricted and Prohibited Substances (Appendix 2 and 3 Restricted)
Korea (KR) Ministry of Environment (MOE) Designation of Restricted and Prohibited Substances (Appendix 4 and 5 Prohibited)
Korea (KR) South Korea’s National Institute of Environmental Research (NIER) GHS Classifications
Korea (KR) South Korea’s National Institute of Environmental Research (NIER) Registration and Evaluation of Chemicals (K-REACH)
Malaysia (MY) Department of Occupational Safety and Health (DOSH) Classification, Labeling and Safety Data Sheet of Hazardous Chemicals (GHS)
N CoE VOCs
New Zealand (NZ) New Zealand’s Environmental Protection Authority (NZ EPA) GHS Classifications
Philippines (PH) Department of Environment and Natural Resources (DENR) Priority Chemicals List (PCL)
Quebec Commission des normes, de l’équité, de la santé et de la sécurité du travail (CSST) Asthma Agents
Southeast Asia (SEA) Association of Southeast Asian Nations (ASEAN) Cosmetic Directive, List of Permitted UV Filters in Cosmetic Products Annex VII
Southeast Asia (SEA) Association of Southeast Asian Nations (ASEAN) Cosmetic Directive, List of Prohibited Substances Annex II Part 1
Taiwan (Province of China) Ministry of Environment (MOENV) Existing Chemical Substances Subject to Standard Registration under TCCSCA Article 30
Taiwan (Province of China) Ministry of Environment (MOENV) Toxic and Concerned Chemical Substances Control Act – TCCSCA
Taiwan (Province of China) Occupational Safety and Health Administration (TOSHA) Occupational Safety and Health Administration (OSHA) GHS Classifications
Thailand (TH) Department of Industrial Works (DIW) Existing Chemicals Inventory (TECI)
Thailand (TH) Department of Industrial Works (DIW) Thai Ministerial Regulation on Hazardous Substances for Industrial Pollution Control – Hazardous Substances Act (HSA)
United Arab Emirates (UAE) Saudi Standards, Metrology and Quality Organization (SASO) Restriction of Hazardous Substances in Electrical and Electronic Equipment (RoHS)
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) CERCLA Priority List of Hazardous Substances
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Carcinogenicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Dermal Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Developmental Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Endocrine Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Gastrointestinal Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Hematological Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Hepatotoxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Immunological Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Lymphoreticular Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Musculoskeletal Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Neurotoxicants
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Ocular Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Renal Toxicity
United States of America (the) Agency for Toxic Substances and Disease Registry (ATSDR) Health Effects Associated with Respiratory Toxicity
United States of America (the) American Conference of Governmental Industrial Hygienists (ACGIH) Biological Exposure Indices (BEIs) Notice of Intended Changes 2023
United States of America (the) American Conference of Governmental Industrial Hygienists (ACGIH) Chemical Substances and Other Issues Under Study (TLV®-CS) 2023
United States of America (the) Association of Occupational and Environmental Clinics (AOEC) Asthmagens
United States of America (the) California Air Resources Board (CARB) Toxic Air Contaminants
United States of America (the) California Department of Public Health (CDPH) Biomonitoring California Priority Chemicals
United States of America (the) California Department of Public Health (CDPH) Reportable Ingredients List under the Safe Cosmetics Act
United States of America (the) California Department of Toxic Substances Control (DTSC) Safer Consumer Products Candidate Chemicals Full Candidate Chemical List
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Cancer Potency Factors and Unit Risk Values Related to the Air Toxic Hot Spots Program
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Chemicals with California Office of Environmental Health Hazard Assessment Reference Exposure Levels (RELs)
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Proposition 65 Carcinogenicity
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Proposition 65 Chemicals with No Significant Risk Levels (NSRLs) Maximum Allowable Dose Levels (MADLs)
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Proposition 65 Developmental Toxicity
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Proposition 65 Reproductive Toxicity Female
United States of America (the) California EPA Office of Environmental Health Hazard Assessment (OEHHA) Proposition 65 Reproductive Toxicity Male
United States of America (the) California State Assembly Bill No. 312 Safe Cosmetics Act
United States of America (the) California State Assembly Bill No. 496 Ingredients Banned in Cosmetics
United States of America (the) California State Water Resources Control Board (SWRCB) California Priority Toxic Pollutants
United States of America (the) California State Water Resources Control Board (SWRCB) Chemicals with Maxiumum Contaminant Levels (MCLs)
United States of America (the) California State Water Resources Control Board (SWRCB) Chemicals with Notification Levels
United States of America (the) Campaign for Safe Cosmetics’ Red List: TIER 1
United States of America (the) Campaign for Safe Cosmetics’ Red List: TIER 1A
United States of America (the) Campaign for Safe Cosmetics’ Red List: TIER 2
United States of America (the) Campaign for Safe Cosmetics’ Red List: TIER 3
United States of America (the) Consumer Product Safety Commission (CPSC) Strong Sensitizers
United States of America (the) Consumer Product Safety Commission Supplemental Precautionary Labeling Required Substances
United States of America (the) Cosmetic Ingredient Review (CIR) 2022–2025 Priority List with Ingredient Groups
United States of America (the) Department of Homeland Security (DHS) Appendix A Chemicals of Interest – COI List
United States of America (the) Environmental Protection Agency (US EPA) 20 high priority chemicals under TSCA
United States of America (the) Environmental Protection Agency (US EPA) Active Ingredients Permitted in Exempted Minimum Risk Pesticide Products under FIFRA Law Part 152B Table 1
United States of America (the) Environmental Protection Agency (US EPA) Certain Chemical Substances and Mixtures under TSCA Section 6
United States of America (the) Environmental Protection Agency (US EPA) Chemical Action Plans (EPA Action)
United States of America (the) Environmental Protection Agency (US EPA) Clean Water Act Priority Pollutants
United States of America (the) Environmental Protection Agency (US EPA) Exempt VOCs
United States of America (the) Environmental Protection Agency (US EPA) Extremely Hazardous Substances
United States of America (the) Environmental Protection Agency (US EPA) Formaldehyde Standards for Composite Wood Products (Title VI)
United States of America (the) Environmental Protection Agency (US EPA) Global Warming Potentials under Greenhouse Gas Reporting Program 40 CFR Part 98
United States of America (the) Environmental Protection Agency (US EPA) Hazardous Air Pollutants (HAPs)
United States of America (the) Environmental Protection Agency (US EPA) Inert Ingredients Permitted in Minimum Risk Pesticide Products under FIFRA Law Part 152B Table 2
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) 2005 Carcinogenic
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) 2005 Suggested Carcinogenic
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1986 A
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1986 B1
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1986 B2
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1986 C
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1996 Known/Likely
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1999 Carc
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1999 Likely Carcinogenic
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 1999 Suggested Carcinogen
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens (EPA C) 2005 Likely Carcinogenic
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Carcinogens All
United States of America (the) Environmental Protection Agency (US EPA) Integrated Risk Information System (IRIS) Neurotoxicants
United States of America (the) Environmental Protection Agency (US EPA) List of Extremely Hazardous Substances under the Emergency Planning and Community Right-to-Know Act 40 CFR Part 355
United States of America (the) Environmental Protection Agency (US EPA) Ozone Depleting Substances (EPA-ODS) Class 1
United States of America (the) Environmental Protection Agency (US EPA) Ozone Depleting Substances (EPA-ODS) Class 2
United States of America (the) Environmental Protection Agency (US EPA) Persistent, Bioaccumulative, and Toxic (PBT) Chemicals under TSCA
United States of America (the) Environmental Protection Agency (US EPA) Polycyclic Aromatic Hydrocarbons (PAHs)
United States of America (the) Environmental Protection Agency (US EPA) Priority Persistent, bioaccumulative and toxic substances PBTs (National Waste Minimization Program (NWMP) Priority)
United States of America (the) Environmental Protection Agency (US EPA) Proposed 20 Low-Priority Substances under the Toxic Substances Control Act (TSCA)
United States of America (the) Environmental Protection Agency (US EPA) Reactivity Factors Associated with Volatile Organic Compound Emission under the Air Program 40 CFR Part 59
United States of America (the) Environmental Protection Agency (US EPA) Resource Conservation and Recovery Act (RCRA) Hazardous Waste
United States of America (the) Environmental Protection Agency (US EPA) Resource Conservation and Recovery Act (RCRA) Toxic Waste
United States of America (the) Environmental Protection Agency (US EPA) Risk Management Program (RMP) Rule
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Antimicrobial Actives
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Chelating Agents
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Colorants
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Defoamers
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Emollients
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Enzymes and Enzyme Stabilizers
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Fragrances
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Full Green Circle
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United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Oxidants and Oxidant Stabilizers
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Polymers
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Preservatives and Antioxidants
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United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Skin Conditioning Agents
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United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Specialized Industrial Chemicals
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Surfactants
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Uncategorized
United States of America (the) Environmental Protection Agency (US EPA) Safer Chemical Ingredient List Yellow Triangle
United States of America (the) Environmental Protection Agency (US EPA) Tolerance Exemptions for Active and Inert Ingredients in Food-Contact Sanitizing Solutions under FFDCA Part 180.940
United States of America (the) Environmental Protection Agency (US EPA) Tolerance Exemptions for Minimal Risk Active and Inert Ingredients under under FFDCA Part 180.950
United States of America (the) Environmental Protection Agency (US EPA) Tolerance Exemptions for Polymers as Inert Ingredients in a Pesticide Chemical Formulation under FFDCA Part 180.960
United States of America (the) Environmental Protection Agency (US EPA) Toxic Release Inventory (TRI) Program
United States of America (the) Environmental Protection Agency (US EPA) Toxics Release Inventory Persistent, bioaccumulative and toxic substances (TRI PBT)
United States of America (the) Environmental Protection Agency (US EPA) first 10 chemicals under TSCA
United States of America (the) Environmental Protection Agency (US EPA) non-confidential Toxic Substances Control Act (TSCA) Chemical Substance Inventory
United States of America (the) Environmental Protection Agency (US EPA) the Fifth Drinking Water Contaminate Candidate list (CCL 5)
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Cosmetics and Exempt from Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Cosmetics and Required for Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Devices and Exempt from Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Devices and Required for Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Drugs and Exempt from Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Drugs and Required for Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Food and Exempt from Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Approved for Use in Food and Required for Batch Certification
United States of America (the) Food and Drug Administration (FDA) Color Additives Not Permitted for Any Use
United States of America (the) Food and Drug Administration (FDA) Generally Regarded as Safe (GRAS) List of Food Additives
United States of America (the) Food and Drug Administration (FDA) Indirect Additives Used in Food Contact Substances
United States of America (the) Food and Drug Administration (FDA) Inventory of Environmental Impact Decisions for Food Contact Substance Notifications
United States of America (the) Food and Drug Administration (FDA) Substances Determined Not to Be GRAS in Post-Market Evaluations
United States of America (the) Green Building Council (USGBC) Substance to avoid to fulfill LEED Pilot Credit 54 Option 1
United States of America (the) Maine Department of Environmental Protection (DEP) Chemicals of High Concern in Children’s Products
United States of America (the) Maine Department of Environmental Protection (DEP) Safer Chemicals in Children’s Products Regulated Priority Chemicals
United States of America (the) Maine State Legislature (MSL) Safe Cosmetics Act under Revised Statutes Title 22 Chapter 37
United States of America (the) Massachusetts Toxics Use Reduction Institute (TURI) Toxics Use Reduction Act (TURA) PFAS categories
United States of America (the) Minnesota Department of Health (MDH) Department of Health Chemicals of High Concern and Priority Chemicals
United States of America (the) National Institute for Occupational Safety and Health (NIOSH) Occupational Carcinogens
United States of America (the) National Oceanic and Atmospheric Administration (NOAA) Screening Quick Reference Tables for Inorganics in Sediments
United States of America (the) National Oceanic and Atmospheric Administration (NOAA) Screening Quick Reference Tables for Inorganics in Soil
United States of America (the) National Oceanic and Atmospheric Administration (NOAA) Screening Quick Reference Tables for Inorganics in Water
United States of America (the) National Oceanic and Atmospheric Administration (NOAA) Screening Quick Reference Tables for Organics in Sediments
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Clear Evidence of Adverse Effects Developmental Toxicity
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Clear Evidence of Adverse Effects Reproductive Toxicity
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Limited Evidence of Adverse Effects Reproductive Toxicity
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Report on Carcinogens Known To Be Human Carcinogens
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Report on Carcinogens Reasonably Anticipated To Be Human Carcinogens
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Some Evidence of Adverse Effects Developmental Toxicity
United States of America (the) National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Some Evidence of Adverse Effects Reproductive Toxicity
United States of America (the) New York State Senate Toxic Chemicals in Children’s Products under Environmental Conservation Law
United States of America (the) Occupational Safety and Health Administration (OSHA) Carcinogens
United States of America (the) Occupational Safety and Health Administration (OSHA) Limits for Air Contaminants 29 CFR 1910.1000 Table Z-1
United States of America (the) Occupational Safety and Health Administration (OSHA) Limits for Air Contaminants 29 CFR 1910.1000 Table Z-2
United States of America (the) Occupational Safety and Health Administration (OSHA) Limits for Air Contaminants 29 CFR 1910.1000 Table Z-3
United States of America (the) Occupational Safety and Health Administration (OSHA) List of Highly Hazardous Chemicals, Toxics and Reactives 29 CFR 1910.119 Appendix A
United States of America (the) Oregon Department of Environmental Quality (DEQ) Priority Persistent Pollutants (P3) List
United States of America (the) Oregon Health Authority (OHA) High priority chemicals of concern to children’s health
United States of America (the) United States of America (the) Food and Drug Administration (FDA) Antimicrobials Banned in Antiseptic Washes
United States of America (the) Vermont Department of Health (VDH) Chemicals of High Concern to Children
United States of America (the) Washington State Department of Ecology (Ecology) Chapter 173-339 WAC – Cosmetic Products Restrictions (Formaldehyde in Cosmetics)
United States of America (the) Washington State Department of Ecology (Ecology) Chemicals of High Concern to Children (CCHC)
United States of America (the) Washington State Department of Ecology (Ecology) Chemicals of High Concern to Children (CCHC) (Enhesa Expanded)
United States of America (the) Washington State Department of Ecology (Ecology) PBT Metals of Concern
United States of America (the) Washington State Department of Ecology (Ecology), Persistent, Bioaccumulative, and Toxic Substances
United States of America (the)National Toxicology Program (NTP) Office of Health Assessment and Translation (OHAT) Limited Evidence of Adverse Effect Developental Toxicity
United States of American (the) Environmental Protection Agency (US EPA) Priority Persistent, bioaccumulative and toxic substances PBTs
Viet Nam (VN) Chemicals Agency Law on Management of Chemicals: Annex 2 List of Restricted Substances
Viet Nam (VN) Vietnam Chemicals Agency (VCA) National Chemical Inventory